The Military and Hospitaller Order of Saint Lazarus of Jerusalem has a long historical tradition dating back to the 12th century. In contrast, the Maltese jurisdiction has a history ranging for only six decades being established in 1964. In spite of its relatively short history and limited membership base, the jurisdiction quickly became central to the management of the International Order. This work looks at the developmental history and reviews broadly the philanthropic activities of the national jurisdiction, besides also reviewingthe history of its sister 'magisterial' jurisdiction also based in Malta - the Grand Commandery of the Castello.