Tyndall moved in the highest social and intellectual circles. A friend of Tennyson and Carlyle, as well as Michael Faraday and Thomas Huxley, Tyndall was one of the most visible advocates of a scientific world view as tensions grew between developing scientific knowledge and theology. He was an active and often controversial commentator, through letters, essays, speeches, and debates, on the scientific, political, and social issues of the day, with strongly stated views on Ireland, religion, race, and the role of women. Widely read in America, his lecture tour there in 1872-73 was a great success.

Roland Jackson paints a picture of an individual at the heart of Victorian science and society. He also describes Tyndall's importance as a pioneering mountaineer in what has become known as the Golden Age of Alpinism. Among other feats, Tyndall was the first to traverse the Matterhorn. He presents Tyndall as a complex personality, full of contrasts, with his intense sense of duty, his deep love of poetry, his generosity to friends and his combativeness, his persistent ill-health alongside great physical stamina driving him to his mountaineering feats. Drawing on Tyndall's letters and journals for this first major biography of Tyndall since 1945, Jackson explores the legacy of a man who aroused strong opinions, strong loyalties, and strong enmities throughout his life.