Colorectal Cancer Treatment Resistance: Mechanisms, Insights, Advances and Solutions provide insights, knowledge, and potential solutions for healthcare professionals, researchers, and individuals affected by colorectal cancer. The book discusses innovative therapies, personalised medicine, and the latest scientific advancements in the field, all aimed at enhancing the effectiveness of treatment and improving the prognosis for colorectal cancer patients. In 17 chapters this book contributes to the ongoing efforts to understand and address treatment resistance in cancer, which is a critical issue in oncology. It is part of the broader context of cancer research and treatment strategies, with the potential to impact the overall approach to managing colorectal cancer and, by extension, other types of cancer that may exhibit similar resistance challenges. By studying and addressing resistance mechanisms, researchers and healthcare professionals can work towards improving patient outcomes and the overall quality of cancer care.