In Pen and Ink Witchcraft, eminent Native American historian Colin G. Calloway narrates the history of diplomacy between North American Indians and their imperial adversaries, particularly the United States. Treaties were cultural encounters and human dramas, each with its cast of characters and conflicting agendas. Many treaties, he notes, involved not land, but trade, friendship, and the resolution of disputes. Far from all being one-sided, they were negotiated on the Indians' cultural and geographical terrain. When the Mohawks welcomed Dutch traders in the early 1600s, they sealed a treaty of friendship with a wampum belt with parallel rows of purple beads, representing the parties traveling side-by-side, as equals, on the same river. But the American republic increasingly turned treaty-making into a tool of encroachment on Indian territory. Calloway traces this process by focusing on the treaties of Fort Stanwix (1768), New Echota (1835), and Medicine Lodge (1867), in addition to such events as the Peace of Montreal in 1701 and the treaties of Fort Laramie (1851 and 1868). His analysis demonstrates that native leaders were hardly dupes. The records of negotiations, he writes, show that "Indians frequently matched their colonizing counterparts in diplomatic savvy and tried, literally, to hold their ground."

Each treaty has its own story, Calloway writes, but together they tell a rich and complicated tale of moments in American history when civilizations collided.