The scenes in Site Lines: Lost New York, 1954-2022 extend from Midtown South, home of the artist from the mid-1940s to the mid-1960s, to the Upper East Side, where she and her family lived in a historic Rhinelander townhouse. Along the way she passes through Midtown, including storied Fifth Avenue and the Theater District, and the Upper West Side.

Her work includes buildings both important and unimportant that would otherwise have been lost to memory: the glorious Helen Hayes Theater, the Art Deco Horn & Hardart Automat on 57th Street, and blocks upon blocks of ordinary yet distinctive retail and commercial structures. In addition, Gill includes buildings that have themselves been quietly observing the changing city, often changing along with it: St. Bart's, the Villard Houses, and MoMA before it "ate" 53rd Street. Each scene is accompanied by text that blends in-depth research with first-hand observation.