St. Louis is a vicious town. Filled with crime, sex, drugs, murder, money, and consciousness. Poison floating in the air, contagious to anyone who steps within the atmosphere. In a society of sickness, Isaiah tests his immunity. His best friend Wardell is already infected, and not shy about sharing his illness. Isaiah has seen all facets of his city. He's lived all of what the city has to offer, including the "so called" superior option. He went off to school and saw a different side of life, and is now trying to heal an infected city. This proves to be a tougher task than expected with the twists and turns that affect his life in the coming days. Can he make a difference? Or will he be swallowed by the Blues of St. Louis.