Jason Wilson explores the 5,000-mile chain of volcanoes, deep valleys, and upland plains, revealing the Andes' mystery, inaccessibility, and power through the insights of chroniclers, scientists, and modern-day novelists. His account starts at sacred Cuzco and Machu Picchu, moves along imagined Inca routes south to Lake Titicaca, La Paz, Potosí, and then follows the Argentine and Chilean Andes to Patagonia. It then moves north through Chimborazo, Quito, and into Colombia, along the Cauca Valley up to Bogotá and east to Caracas.

Looking at the literature inspired by the Andes as well as its turbulent history, this book brings to life the region's spectacular landscapes and the many ways in which they have been imagined.