Muro's father, believing that the Disagreement will pass, sends his son instead to Charlottesville. Jefferson's forty-year-old University of Virginia has become a haven of rogues and dilettantes, among them Muro's roommate, Braxton Baucom III, a planter's son who attempts to strike a resemblance to General "Stonewall" Jackson. Though the pair toasts lightheartedly "To our studies!" with a local corn whiskey known as "The Bumbler," the war effort soon exerts a sobering influence. Medical students like Muro are pressed into service at the Charlottesville General Hospital, where the inexperienced Dr. Muro saves the life of a Northern lieutenant, earning the scorn of his peers.

As the war progresses, Muro takes up yet another cause -- winning the affections of the beguiling Miss Lorrie Wigfall. Here, too, Muro faces a cunning adversary. Just as the fighting is closing in, Muro is forced to make a choice that will shape the rest of his life. In this story of love, loyalty, and unimaginable sacrifice, a doctor struggles to balance the passions of youth with the weight of responsibility.