Lucia Scardina, a beautiful student and artist model, is missing. After her desperate mother visits a medium who tells her Lucia fled to Chicago to hide from something and is now dead, she vows vengeance for those responsible.

Decades later, a young artist brings a mysterious painting by his grandfather, renowned portrait artist, Lawrence Taylor, to Dr. Bruce Mallory who has just completed testing of cutting-edge technology designed to help identify certain art techniques. When an extensive infrared scan is performed on the painting, it is discovered that a portrait of long-missing Lucia lies underneath. Even more perplexing yet is the fact that the painting seems to take on a life of its own as long-held secrets and desires from the past are revealed. As a high-level scientist develops an unhealthy obsession with what is transpiring within Mallory's projection room, Lucia waits to tell her story.

In this art history thriller, supernatural forces activated by a grieving mother long ago combine with a modern day scientist's manipulations to create havoc as a doctor and a young artist attempt to solve the mystery behind a painting.